CORDIS Project
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The AUTO-SELECT project aims to identify key substrates involved in the autophagy process across different organs and understand the signaling mechanisms that influence their selection. It utilizes advanced mouse models and -omic technologies to explore how selective autophagy can be modulated for potential therapeutic…
(Macro)autophagy is an evolutionarily conserved catabolic process induced to preserve cellular homeostasis under conditions of stress, such as nutrient starvation.
Upon autophagy activation cellular components are engulfed by autophagic vesicles, which then fuse with lysosomes for substrate degradation.
Despite the unquestionable physiological and medical relevance of nutrient- and pharmacological-induction of autophagy in human health, the precise identity of autophagy substrates and the rules…
UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Italy, Roma
Type: Research institute
Activity type: Research Organisations
SME: No
Italy, Pozzuoli
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
NEXT GENERATION DIAGNOSTIC SRL
Italy, Pozzuoli
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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