CORDIS Project
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This project investigates a newly identified pathway called autoxitus, which enables the secretion of autophagosomes from cells. It aims to understand the molecular mechanisms behind this process and its implications for cellular communication and stress signaling, particularly in the context of viral infections and pr…
Cells control their content by balancing its synthesis and degradation.
Autophagy is a key degradation process capable of engulfing large fractions of cells, including organelles, into double-membrane vesicles called autophagosomes.
These fuse with lysosomes causing degradation of their cargo.
Secretory pathways, including secretory autophagy, offer an alternative option to remove unwanted materials from cells.
However, mechanisms allowing the secretion of larger cellular components are still un…
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
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