CORDIS Project
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This project explores the molecular interactions within the neuromuscular unit to understand neuromuscular disorders. By using advanced imaging and mouse models, it aims to reveal how local glial cell dysfunction affects motor function and to identify potential therapeutic targets.
Neuromuscular disorders belong to the most common but least treatable neurological conditions and are caused by defects in cell types that together build the neuromuscular unit motoneurons and their axons, glial cells and myocytes.
Clinically, neuromuscular diseases share an impairment of motor function and the intimate functional relationship of involved cell types suggests overlapping pathological mechanisms.
As our current understanding is largely confined to locally isolated processes, the…
UNIVERSITAET LEIPZIG
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