CORDIS Project
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This project investigates a new immune pathway involving marginal zone B cells and neutrophils, focusing on how neutrophils can transform into a unique helper cell type that stimulates B cells to produce antibodies. The research aims to uncover mechanisms that could lead to novel vaccine strategies.
The long-term goal of this proposal is to explore a novel immune pathway that involves an unexpected interplay between marginal zone (MZ) B cells and neutrophils. MZ B cells are strategically positioned at the interface between the immune system and the circulation and rapidly produce protective antibodies to blood-borne pathogens through a T cell-independent pathway that remains poorly understood.
We recently found that the human spleen contains a novel subset of B cell helper neutrophils (NBH…
FUNDACIO INSTITUT HOSPITAL DEL MAR D INVESTIGACIONS MEDIQUES
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