CORDIS Project
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This project explores B cell responses to vaccines in both mice and humans, aiming to understand the mechanisms behind memory B cell activation and persistence. It focuses on identifying specific pathways and functions of different B cell subsets to enhance vaccine efficacy.
B cells are the main actors of successful vaccines, and their protective capacity relies on several subsets with innate-like and memory properties that fulfill different effector functions.
In the present project, we wish to develop approaches in both mice and humans, to confront the similarities and the differences of their B cell responses.
The three aims proposed are:1) To study the different B cell subsets and TFH cells engaged in a memory response through the use of a new mouse reporter lin…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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