CORDIS Project
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BacTheRNA focuses on developing innovative circular RNA-based therapeutics using food-grade bacteria to address production costs and delivery challenges. By leveraging the stability and scalability of circular RNAs, the project aims to create effective treatments for Type 2 Diabetes Mellitus and other diseases.
RNA therapeutics are a rapidly growing field of research, thanks to their enormous potential.
However, production costs and delivery systems represents the major issues for their widespread use in clinics.
BacTheRNA aims at overcoming these issues by developing novel circular RNA (circRNA)-based therapeutics using recombinant food-grade bacteria.
CircRNAs are advantageous over their linear counterpart, for their stability due to their intrinsic resistance to nucleases (which cannot cut circular…
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
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