CORDIS Project
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The BActin project investigates how bacteria shape themselves, focusing on the role of the cell wall and the MreB protein in rod-shaped bacteria. It combines advanced microscopy and genetic techniques to understand bacterial growth and develop new antibiotic screening methods.
One of the ultimate goals in cell biology is to understand how cells determine their shape.
In bacteria, the cell wall and the actin-like (MreB) cytoskeleton are major determinants of cell shape.
As a hallmark of microbial life, the external cell wall is the most conspicuous macromolecule expanding in concert with cell growth and one of the most prominent targets for antibiotics.
Despite decades of study, the mechanism of cell wall morphogenesis remains poorly understood.
In rod-shaped bacteria,…
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
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