CORDIS Project
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This project investigates asymmetric cell division in budding yeast, focusing on how mother cells create diverse daughter cells through molecular barriers. These barriers influence the inheritance of cellular components, aging, and differentiation, providing insights into cellular diversity and adaptation mechanisms.
Asymmetric cell division is a key mechanism for the generation of cell diversity in eukaryotes.
During this process, a polarized mother cell divides into non-equivalent daughters.
These may differentially inherit fate determinants, irreparable damages or age determinants.
Our aim is to decipher the mechanisms governing the individualization of daughters from each other.
In the past ten years, our studies identified several lateral diffusion barriers located in the plasma membrane and the endopla…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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