CORDIS Project
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This project aims to develop a framework for integrating diverse structural data from biological macromolecular assemblies using Bayesian probability theory. It focuses on improving molecular modeling techniques to accurately determine the structures of complex proteins and their interactions across multiple scales.
The functioning of a single cell or organism is governed by the laws of chemistry and physics.
The bridge from biology to chemistry and physics is provided by structural biology: to understand the functioning of a cell, it is necessary to know the atomic structure of macromolecular assemblies, which may contain hundreds of components.
To characterise the structures of the increasingly large and often flexible complexes, high resolution structure determination (as was possible for example for the…
INSTITUT PASTEUR
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