CORDIS Project
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This project focuses on developing a new strategy for synthesizing complex natural products known as polypropionates, which have various biological activities. It aims to enhance the efficiency of creating these compounds for therapeutic and biomedical applications.
Amongst all natural products, polyketides constitute a very important class due to their broad spectrum of biological activities (eg. antibiotic, antitumoral, antifungal, antiparasitic).
Many of these compounds are referred to as polypropionates, which are characterized by sequences of methyl- and hydroxy-bearing stereogenic centres, enabling large numbers of possible stereochemical permutations.
The importance of these natural products as therapeutic agents and as biomedical tools together with…
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