CORDIS Project
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This project aims to develop an early detection system for neurological disorders like Alzheimer's and Parkinson's using microfluidic aggregation assays. By analyzing biological samples, the technology seeks to provide insights into disease progression and potential diagnostic applications.
There is currently no early detection system for neurological protein misfolding disorders (such as Alzheimer's and Parkinson's diseases) that would satisfy the demands for rapid, quantitative, flexible, and reproducible assays to study amyloidogenesis in biological samples.
We will explore the potential of aggregation assays in microdroplets that are formed in microfluidic devices.
We have found that the readout of this assay reflects the disease progression, when samples of Drosophila fruit fl…
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