CORDIS Project
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This project explores the activation of B cells and the formation of tertiary lymphoid structures using advanced materials. By employing nano- and biomaterials, it aims to enhance anti-cancer immunity and develop innovative immunotherapeutic strategies for cancer treatment.
Recent clinical evidence points to a potential new direction in immuno-oncology: utilizing B cells and B cell-associated tertiary lymphoid structures (TLS). B cells display diverse immunological actions, including antibody production, antigen presentation, cytokine secretion and TLS induction.
They have a dual role: they can initiate and reinforce anti-cancer immunity but B cells can also acquire regulatory phenotypes.
To open up a new immunotherapeutic paradigm, I aim to understand how to optim…
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