CORDIS Project
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This project focuses on understanding the role of epigenetic silencing in gene expression and its implications for cancer. By studying specific proteins involved in chromatin structure, it aims to identify new therapeutic targets for cancer treatment.
Epigenetic silencing is essential for modulating gene expression patterns in developing organisms and has very big impact on the genome integrity.
Cancer, as well as many other diseases, has been linked to the changes in transcription of regulatory genes due to the aberrant epigenetic silencing.
Despite many epigenetic regulators, enzymes including histone deacetylases, methyltransferases, and DNA methyltransferases, were discovered, it is critical to bridge the gap in our understanding of the…
THE UNIVERSITY OF EDINBURGH
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