CORDIS Project
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This project focuses on a novel imaging technique to study calcium signaling in pancreatic beta-cells using the eye as a non-invasive observation window. It aims to understand how calcium dynamics affect insulin secretion and identify potential targets for diabetes treatment.
The challenge in cell physiology/pathology today is to translate in vitro findings to the living organism.
We have developed a unique approach where signal-transduction can be investigated in vivo non-invasively, longitudinally at single cell resolution, using the anterior chamber of the eye as a natural body window for imaging.
We will use this approach to understand how the universally important and highly complex signal Ca2+ is regulated in the pancreatic beta-cell, while localized in the vas…
KAROLINSKA INSTITUTET
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