CORDIS Project
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The betaPPreg project investigates how maternal insulin-producing cells adapt during pregnancy using pigs as a model. It aims to identify the mechanisms behind beta-cell expansion to better understand gestational diabetes and develop potential treatments.
Pregnancy is characterized by the development of maternal insulin resistance and increased hepatic glucose production to provide sufficient glucose to be used as nutrient by the developing fetus.
The maternal insulin-producing beta-cells expand to counterbalance the increased glucose levels and failure of this process can lead to development of gestational diabetes, which has great health implications for both the mother and the developing fetus.
Yet, our knowledge on the mechanisms behind the p…
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
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