CORDIS Project
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This project investigates the regeneration of pancreatic alpha-cells into beta-like cells to reverse Type 1 diabetes. By understanding the mechanisms behind this conversion, the research aims to develop new therapeutic strategies for diabetes treatment.
Diabetes has become one of the most widespread metabolic disorders with epidemic dimensions affecting almost 6% of the world’s population.
Despite modern treatments, the life expectancy of patients with Type 1 diabetes remains reduced as compared to healthy subjects.
There is therefore a need for alternative therapies.
Towards this aim, using the mouse, we recently demonstrated that the in vivo forced expression of a single factor in pancreatic alpha-cells is sufficient to induce a continuous re…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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