CORDIS Project
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This project aims to develop microfluidic devices that enable biological assays on a chip, facilitating high-throughput screening for drug discovery and protein engineering. It focuses on creating isolated reaction compartments to optimize sample use and assay efficiency.
The vision of putting a lab on a chip has far reaching implications for biological research.
Microfluidic systems can now be built that - for example in past research by the applicant - can be used for protein crystallisation with only minute amount of precious proteins. A second challenge is to carry out functional biological assays on a chip.
Such assays are used in high-throughput screening, e.g. for novel drug molecule or protein mutants with improved properties for directed evolution of fun…
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