CORDIS Project
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This project explores how the microenvironment of neural stem cells influences their behavior, particularly in terms of cell division. By creating artificial niches, it aims to understand the signals that regulate stem cell fate, enhancing potential clinical applications.
Although neural stem cells (NSC) have been isolated successfully and characterized relatively extensively, little is known about the role of their natural microenvironment, the so-called niche, in influencing their behavior.
The role of distinct niche signals and their spatial orientation in regulating the choice between quiescence, self-renewal or differentiation is poorly understood, due in part to a lack of suitable in vitro model systems.
The main goal of the proposed project is to investiga…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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