CORDIS Project
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This project investigates a new method for delivering drugs to treat bacterial biofilms, which are resistant to conventional treatments. By developing advanced drug-encapsulating vehicles, the project aims to enhance the effectiveness of therapies for infections in humans and on contaminated medical devices.
Bacterial biofilms are widespread, both as infections in humans and on devices that have come in contact with infected tissue, and pose a major health and economic burden.
Such biofilms are difficult to treat as they present strong resistance to drug delivery, due to a dense, hydrated polysaccharide/protein matrix in which the bacterial communities encase themselves, and from the bacterial membrane itself.
Liposomes stabilized by poly(ethylene glycol), PEG moieties, the current gold-standard and…
WEIZMANN INSTITUTE OF SCIENCE
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