CORDIS Project
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This project develops chemical technologies for non-invasive detection of gene expression and microRNA sequences in living organisms. It also explores carbohydrate recognition through organized peptide nucleic acid architectures, aiming to improve understanding of biological interactions and potential therapeutic appli…
The overall objective of the proposal is to develop enabling chemical technologies to address two important problems in biology: detect in a nondestructive fashion gene expression or microRNA sequences in vivo and, secondly, study the role of multivalency and spatial organization in carbohydrate recognition.
Both of these projects exploit the programmable pre-organization of peptide nucleic acid (PNA) to induce a chemical reaction in the first case or modulate a ligand-receptor interaction in th…
UNIVERSITE DE STRASBOURG
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