CORDIS Project
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This project explores the mechanics of epithelial tissue formation, focusing on how cells change shape during development. By studying early fruit fly embryogenesis, it aims to uncover the biochemical and mechanical principles that govern tissue morphogenesis and how these processes are coordinated at the cellular leve…
Tissue morphogenesis is a complex process that emerges from spatially controlled patterns of cell shape changes.
Dedicated genetic programmes regulate cell behaviours, exemplified in animals by the specification of apical constriction in invaginating epithelial tissues, or the orientation of cell intercalation during tissue extension.
This genetic control is constrained by physical properties of cells that dictate how they can modify their shape. A major challenge is to understand how biochemica…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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