CORDIS Project
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This project investigates the dynamics of a specific bacteriophage, Herelleviridae phage phi812, in biofilms of the antibiotic-resistant bacterium Staphylococcus aureus. By utilizing advanced imaging techniques, the research aims to understand how phages interact with bacterial cells, potentially leading to improved ph…
In 2017, the World Health Organization declared Staphylococcus aureus to be an antibiotic-resistant pathogen for which new therapeutics are urgently needed.
Upon infection, S. aureus forms biofilms that can only be treated by the long-term application of several antibiotics in high doses or the surgical removal of the infected tissues.
An alternative approach, phage therapy, has not been approved for clinical use, because the effects of phage infection on a biofilm are not sufficiently character…
Masarykova univerzita
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