CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates how rest periods after mechanical stress affect heart cell adaptation, aiming to improve understanding of heart failure mechanisms. It examines the role of specific proteins in gene expression related to heart health, particularly under different stress conditions.
In Europe about 4 million people die every year from cardiovascular diseases.
The mechanisms underlying heart failure are still poorly understood.
Experiments proposed here test the hypothesis that periods of rest following mechanical stress result in a more physiological adaptation in cardiac myocytes, compared with continuous stress, which leads to pathological adaptation.
Adaptation is proposed to be mediated, at least in part, by nucleo-cytoplasmic shuttling proteins which translocate to the…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
