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The BoneScreen project aims to create a high-content screening platform to identify drugs that affect bone remodeling, addressing bone diseases like osteoporosis. It utilizes a 3D osteochondral system to better mimic bone cell interactions and reduce animal testing.
Drug development remains a long and costly process with low success rates in clinical trials.
While a majority of cell-based compound screenings are still based on 2D experiments, compelling evidence suggests that 3D culture technologies will accommodate for a better precision in drug discovery.
On the other hand, such screening cultures are particularly challenging in terms of 3D visualization.
In the BoneScreen project, we propose to develop a high content screening (HCS) platform capable of i…
TECHNISCHE UNIVERSITEIT EINDHOVEN
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