CORDIS Project
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The BOOSTB4 project aims to evaluate the safety and effectiveness of transplanting fetal mesenchymal stem cells in patients with severe osteogenesis imperfecta, a genetic disorder causing brittle bones. The project includes a clinical trial to assess outcomes related to fracture frequency and quality of life.
Osteogenesis imperfecta (OI) is, in its severe forms, a devastating inherited disorder characterised by brittle bones. A person with severe OI is affected throughout their lifetime with repeated, multiple fractures, considerable pain and handicap.
There is no curative or effective treatment for OI.
Our preclinical studies and initial clinical cases have demonstrated that transplantation of fetal mesenchymal stem cells (MSC) is a promising approach for treatment of OI.
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KAROLINSKA INSTITUTET
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Sweden, Stockholm
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SME: No
United Kingdom, London
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Leiden University Medical Center
Netherlands, Leiden
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
KLINIKUM DER UNIVERSITAET ZU KOELN
Germany, Koeln
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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