CORDIS Project
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This project explores advanced methods for creating single enantiomers in organic synthesis using enantioselective catalysis. It aims to expand the use of non-stabilized nucleophiles in dynamic kinetic asymmetric transformations to improve the efficiency of chemical reactions.
The formation of carbon-carbon bonds in an asymmetric fashion is a very useful process in synthetic chemistry, since it generates single enantiomers of chiral molecules at the same time as the molecular framework is being assembled.
In this context, two strategies for the generation of single enantiomer compounds using enantioselective catalysis have been widely emabraced: on the one hand, the use of prochiral substrates, and on the other hand, the use of racemic substrates in enantiomer resolut…
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