CORDIS Project
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This project focuses on developing new methods for creating borylated molecules, which are essential in organic synthesis. By introducing novel boryl radical precursors, it aims to enhance the production of three-dimensional molecules for pharmaceutical applications.
Borylated molecules are some integral tools routinely used to aid molecular construction in both academia and industry.
Their use in the Nobel Prize-winning Brown oxidation and Suzuki-Miyaura cross-coupling as well as Chan-Lam amination make them ubiquitous in organic synthesis.
The invention of methods to form C–B bonds at sp3 carbons is of strategic importance to facilitate the preparation of saturated, hence 3D, molecules.
As the pharmaceutical sector is aware of the greater clinical success…
RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN
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