CORDIS Project
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This project aims to develop a novel nanoplatform for delivering CRISPR gene editing technology to treat genetic brain diseases. By using insulin to facilitate the transport of CRISPR machinery across the blood-brain barrier, it seeks to enable safe and effective genome editing in specific diseased brain cells.
Genetic brain diseases are among the most devastating and fatal diseases, typically having only palliative treatments and no cure.
The revolutionary CRISPR/Cas gene editing technology provides a new horizon and enormous potential for treating such diseases.
However, efficient and safe delivery of CRISPR machinery to diseased cells within the brain is one of the greatest challenges in medicine today.
Here, I plan to expand far beyond the state-of-the-art, and propose a game-changer approach for t…
BAR ILAN UNIVERSITY
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