CORDIS Project
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This project aims to understand the regenerative capabilities of newts, particularly in the brain, by comparing them to mammals. It focuses on identifying molecular pathways that regulate neurogenesis and exploring the differences in injury responses between these species.
In contrast to mammals, newts possess exceptional capacities among vertebrates to rebuild complex structures, such as the brain.
Our goal is to bridge the gap in the regenerative outcomes between newts and mammals.
My group has made significant contributions towards this goal.
We created a novel experimental system, which recapitulates central features of Parkinson’s disease in newts, and provides a unique model for understanding regeneration in the adult midbrain.
We showed an unexpected but ke…
KAROLINSKA INSTITUTET
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