CORDIS Project
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This project investigates how immune and microbial signals influence brain function through the choroid plexus, a barrier that regulates cerebrospinal fluid. By exploring this communication pathway during development and under varying conditions, the research aims to enhance our understanding of brain regulation and it…
In contrast to other organs, the brain is surrounded by a system of specialized anatomical barriers isolating it from direct contact with immune cells and microbial products present in the blood.
However, such factors do dynamically shape brain function in homeostasis and disease.
Because of this unusual anatomy, the pathways of blood-brain communication are still poorly understood, while this understanding would provide a fundamental insight into brain function regulation, and enrich the curren…
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