CORDIS Project
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This project investigates the role of invariant natural killer T cells in metastatic breast cancer, aiming to understand their impaired function due to cancer-induced immunosuppression. By comparing these cells in patients and healthy individuals, the research seeks to develop new immunotherapy strategies to enhance an…
Breast cancer is the second cause of cancer-related death in women.
Although cancer immunotherapy emerged as a successful therapy for many cancer types, the response of metastatic breast cancer patients to immune checkpoint blockade remains disappointing, urging for a better understanding of the breast cancer immune landscape. iNKT cells are lipid-specific T cells that bridge innate and adaptive immunity and exert a plethora of immune functions depending on tissue distribution.
Despite their kno…
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
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