CORDIS Project
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This project aims to develop mRNA-based therapies for treating severe lung diseases like Surfactant Protein B deficiency and Cystic Fibrosis. It focuses on enhancing lung transfection methods to enable targeted gene correction.
Surfactant Protein B (SP-B) deficiency and Cystic Fibrosis (CF) are severe, fatal inherited diseases affecting the lungs of ten thousands of people, for which there is currently no available cure.
Although gene therapy is a promising therapeutic approach, various technical problems, including numerous physical and immune-mediated barriers, have prevented successful application to date.
My recent studies were the first to demonstrate the life-saving efficacy of repeated pulmonary delivery of chem…
EBERHARD KARLS UNIVERSITAET TUEBINGEN
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