CORDIS Project

Breast Cancer Risk after Diagnostic Gene Sequencing (BRIDGES)

BRIDGES·634935·H2020

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Funding data

Programme: Horizon 2020
Participants: 4
Start - End: 01/09/2015 — 31/08/2021
Status: CLOSED

Summary

This project seeks to identify women at high risk of breast cancer by evaluating DNA variants in known susceptibility genes. It aims to develop a comprehensive risk model and online tools to assist genetic counselors and patients in making informed decisions.

Objective

Breast cancer affects more than 360,000 women per year in the EU and causes more than 90,000 deaths.

Identification of women at high risk of the disease can lead to disease prevention through intensive screening, chemoprevention or prophylactic surgery.

Breast cancer risk is determined by a combination of genetic and lifestyle risk factors.

The advent of next generation sequencing has opened up the opportunity for testing in many disease genes, and diagnostic gene panel testing is being introduc…

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Coordinator

Leiden University Medical Center

ACADEMISCH ZIEKENHUIS LEIDEN

Country: Netherlands, Leiden
Organization type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No

Network and participants(4 participants)

Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom, Cambridge
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
participant
FUNDACION SECTOR PUBLICO ESTATAL CENTRO NACIONAL INVESTIGACIONES ONCOLOGICAS CARLOS III
Spain, Madrid
Type: Research institute
Activity type: Research Organisations
SME: No
participant
LUNDS UNIVERSITET
Sweden, Lund
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
participant
ULEI
Germany, Leipzig
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
participant

4 participants shown of 18

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CORDIS call / funding scheme

Programme: H2020
Call: H2020-PHC-2014-2015
Sub call: H2020-PHC-2014-two-stage
Funding scheme: RIA - Research and Innovation action
Domain note: This block describes the CORDIS project call context. Live open opportunities are managed in the Funding & Tenders domain.

Fields of Science (EuroSciVoc)

Guests see up to 5 EuroSciVoc fields.

Medical and health sciencesBasic medicineMedical genetics
Medical and health sciencesClinical medicineOncologyBreast cancer
Medical and health sciencesHealth sciencesPersonalized medicine
Natural sciencesBiological sciencesGeneticsDNA

Topic

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PHC-05-2014

Keywords

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breast cancer genetic susceptibility lifestyle risk factors predictive testing genetic counselling