CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates G protein coupled receptors (GPCRs) to understand their signaling mechanisms. It employs mutagenesis and biophysical techniques to link receptor conformations to their signaling outcomes, aiming to inform drug design.
G protein coupled receptors (GPCRs) are a class of membrane receptors that transmits extracellular signals into the cell.
They can be activated by a diverse set of ligands including small molecules, hormones, neurotransmitters or photons and are targeted by a third of currently marketed drugs.
Endogenous ligands and drugs may exhibit different efficacy profiles, ranging from full activation to complete inactivation of a signalling pathway.
The key to the selective interaction with signalling par…
UNITED KINGDOM RESEARCH AND INNOVATION
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
United States, Stanford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
