CORDIS Project
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This project focuses on developing mathematical methods to control synthetic gene circuits in growing microbial populations. By accounting for single-cell variability and population dynamics, it aims to enable the design of circuits that function effectively in diverse microbial communities, particularly for bioproduct…
A key turning point in the evolution of life was the transition from single-cell to multicellular organisms and the optimization of fitness via division of labour and specialization.
Similarly, microorganisms have evolved equivalent strategies by forming communities or consortia.
Division of labour in isogenic microbial populations is often implemented by mechanisms that create or act upon population heterogeneity to diversify functionality.
Rational design in synthetic biology, on the other han…
INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET AUTOMATIQUE
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