CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project aims to develop a chemical tool for studying 5-carboxycytosine, a DNA modification involved in epigenetic processes. By creating a method for specific enrichment and sequencing of this modification, it seeks to advance understanding of its biological significance.
5-carboxycytosine (5caC) has been robustly identified in mammalian DNA.
It is known that this DNA modification plays a role in epigenetic demethylation processes.
If 5caC has other epigenetically relevant functions is so far unknown.
Due to its low abundance it is technically challenging to study this modification in biological samples.
Identification of specific readers, recognition by the RNA polymerase II elongation complex, the presence in specific genomic loci as well as changing levels du…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.