CORDIS Project
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This project aims to combat antibiotic resistance by exploring a new family of enzymes involved in natural product biosynthesis. It seeks to develop strategies for modifying these enzymes to create new drug candidates.
The development and spread of antibiotic resistance in microorganisms is a major threat to both humans and animals and the search for new and improved drugs is of high importance.
Natural products are experiencing a strong revival as leads in drug development, and biosynthetic engineering offers sustainable routes to new and potentially improved analogues.
Finding new ways to make these rational changes should ensure that the European Research Area remains competitive in realising the potential…
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