CORDIS Project
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This project investigates how macrophages influence breast cancer cell behavior during metastasis, specifically through interactions involving epidermal growth factor. It aims to clarify the mechanisms of cell movement and invasion in the presence of macrophages.
The leading cause of death for cancer patients is metastasis.
During metastasis, cancer cells interact with various molecules and cells.
It has been shown that a group of macrophages facilitates metastasis.
Our goal is to determine the mechanism of interaction between epidermal growth (EGF) produced by macrophages and epidermal growth factor receptor (EGFR) expressed by breast cancer cells.Soluble EGF or macrophage conditioned medium does not stimulate breast cancer cell invasion into collagen m…
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