CORDIS Project
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The project explores the role of DNA methylation in cancer, focusing on how alterations in this process can serve as biomarkers for early detection and treatment personalization. It employs advanced techniques to profile epigenetic changes in tumors.
Aberrant DNA methylation is the most common molecular lesion of the cancer cell.
Neither gene mutation nor cytogenetic abnormalities are as common in human tumours as DNA methylation alterations.
The stability of our genome and correct gene expression is maintained to a great extent thanks to a perfectly preestablished pattern of DNA methylation and histone modifications.
In cancer this idealistic scenario breaks down due to an interesting phenomenon whereby the regulatory regions (CpG islands)…
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Belgium, Bruxelles / Brussel
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
STICHTING RADBOUD UNIVERSITEIT
Netherlands, Nijmegen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI
Italy, Caserta
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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