CORDIS Project
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This project focuses on understanding cancer evolution by analyzing circulating tumor DNA from metastatic gastro-oesophageal carcinomas. It aims to track changes in cancer populations over time, identify drug resistance mechanisms, and improve clinical insights into cancer dynamics.
The fundamental evolutionary nature of cancer is well recognized but an understanding of the dynamic evolutionary changes occurring throughout a tumour’s lifetime and their clinical implications is in its infancy.
Current approaches to reveal cancer evolution by sequencing of multiple biopsies remain of limited use in the clinic due to sample access problems in multi-metastatic disease.
Circulating tumour DNA (ctDNA) is thought to comprehensively sample subclones across metastatic sites.
However…
QUEEN MARY UNIVERSITY OF LONDON
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United Kingdom, London
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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