CORDIS Project
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This project aims to enhance our understanding of cancer cell metabolism by developing a method to quantify metabolic fluxes in different cellular compartments. By analyzing how cancer cells adapt their metabolism during the cell cycle, the research seeks to identify new targets for cancer therapies.
The metabolism of cancer cells is altered to meet cellular requirements for growth, providing novel means to selectively target tumorigenesis.
While extensively studied, our current view of cancer cellular metabolism is fundamentally limited by lack of information on variability in metabolic activity between distinct subcellular compartments and cells.We propose to develop a spatio-temporal fluxomics approach for quantifying metabolic fluxes in the cytoplasm vs. mitochondria as well as their cel…
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