CORDIS Project
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This project explores cancer signaling pathways using Drosophila as a model organism. It aims to identify new drug targets and regulators through high-throughput screening of RNA interference and small molecule libraries, integrating bioinformatics for better data analysis.
Cancer is often characterized as a disease of signal transduction pathways, since it is frequently associated with inappropriate activation of such pathways.
Indeed, new therapeutic approaches in cancer therapy, such as Herceptin, frequently target signaling pathway components to revert their pathophysiological aberrations.
Most oncogenic pathways have been highly conserved throughout evolution with Drosophila representing a particularly powerful genetic model for the analysis of such signaling…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH
Austria, Wien
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
United Kingdom, Sheffield
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
LONDON
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Spain, Elche
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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