CORDIS Project
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This project explores the cannabinoid CB1 receptor's homodimerization and its interactions with ligands, cholesterol, and a specific protein, CRIP1a. It employs computational modeling and simulations to understand the receptor's behavior, aiming to inform potential treatments for various mental health and metabolic dis…
The cannabinoid CB1 receptor (CB1R) is an attractive molecular target for the treatment of substance abuse, drug addiction, schizophrenia, bipolar disorder, motor dysfunction including Huntington’s disease, as well as cardiometabolic
disease and metabolic syndrome.The general aim of the project is to investigate in silico the phenomenon of the homodimerization of the CB1R, the interaction of the CB1R homodimer with ligands, and to study the effect of membrane
cholesterol and the cannabinoid rec…
UNIVERSITY OF EASTERN FINLAND (UEF)
ITA-SUOMEN YLIOPISTO
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