CORDIS Project
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This project aims to enhance gene therapy and RNA-based treatments by developing a novel isolation technique for adeno-associated viruses using programmable coacervates. This method seeks to improve the purity and yield of these nanoparticles, crucial for effective therapeutic applications.
Gene therapy and RNA-based therapeutics hold significant promise for treating a range of debilitating disorders. A key challenge for these therapies is the effective targeted delivery, which relies on nanovehicles to ensure the stability of the delicate nucleic acids involved.
Biogenic nanoparticles, such as adeno-associated viruses (AAVs), are becoming increasingly promising for these applications, with some AAV-based therapies already receiving regulatory approval.
However, maintaining the phy…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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