CORDIS Project
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The CAR-TIME project aims to enhance cancer immunotherapy by understanding how chimeric antigen receptor T cells interact with the tumor immune microenvironment in lymphoma. By mapping these interactions, the project seeks to identify predictive biomarkers and improve treatment strategies for patients.
Cancer immunotherapies with chimeric antigen receptor (CAR) T cells have shown dramatic clinical efficacy in patients with B cell neoplasms.
Thus, their clinical use is expected to increase considerably in the near future.
However, for poorly understood reasons, not all patients with lymphoma benefit from these expensive therapies.
The ability to stratify patients into probable responders vs. non-responders prior to immunotherapy will improve treatment efficacy, limit patient exposure to adverse…
EBERHARD KARLS UNIVERSITAET TUEBINGEN
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