CORDIS Project
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This project investigates how oxidatively damaged proteins contribute to aging by forming aggregates that damage cellular membranes. It aims to clarify the mechanisms behind age-related cellular dysfunction using advanced imaging and biochemical techniques in both bacterial and mammalian cells.
Aging is one of the greatest mysteries in biology and a considerable contemporary societal challenge.
Despite extensive research, the etiology of aging remains poorly understood.
Most current theories focus on DNA damage as the root cause of aging.
However, this view has been challenged by discovery that oxidative damage to proteins alone is sufficient to recapitulate molecular and cellular hallmarks of aging.
In this project, we aim to elucidate the mechanism through which oxidatively damaged/c…
MEDITERRANEAN INSTITUTE FOR LIFE SCIENCES
MEDITERANSKI INSTITUT ZA ISTRAZIVANJE ZIVOTA
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