CORDIS Project
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This project focuses on the role of a specific protein variant, CnAbeta1, in heart development and embryonic stem cell biology. It aims to understand how changes in CnAbeta1 expression affect heart formation and function, potentially influencing congenital heart defects.
The heart is the first organ to form and it is essential for blood distribution during embryogenesis.
Congenital heart malformations are the most common birth defect in humans, present in 1 % of the human population worldwide.
The calcineurin splicing variant CnAbeta1 is expressed in stem cells, precursors and developing tissues and its expression decreases during tissue maturation.
We aim to determine the role of CnAbeta1 during different stages of embryonic development.
Aims:1.
Identify the ro…
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
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