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The CAREQiPSC project aims to develop effective treatments for osteoarthritis in horses by utilizing induced pluripotent stem cells. It focuses on deriving cartilage from equine stem cells and assessing their therapeutic potential, ultimately contributing to advancements in both veterinary and human medicine.
Osteoarthritis is a degenerative joint pathology that constitutes the first cause of disability in older adults and accounts for >80% of chronic lameness in horses.
Effective treatments are not available while developing them is of utmost importance for the EU objective of translating knowledge into society’s benefit.
Induced pluripotent stem cells (iPSCs) can provide unlimited cells for therapy with no ethical concerns.
However, pre-clinical knowledge is limited to small animals with low transl…
UNIVERSITY OF GALWAY
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