CORDIS Project
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This project explores the interactions between the human gut microbiome and host cells, particularly in relation to diseases like colorectal cancer and inflammatory bowel disease. It employs advanced spatial profiling technologies to map these interactions and predict disease onset.
Microbiome-host crosstalk is crucial for gut homeostasis and its dysregulation is a hallmark of diseases such as colorectal cancer (CRC) and inflammatory bowel disease (IBD).
Despite its key relevance for a holistic understanding of the human superorganism and its (patho-)physiology, how local host-microbiome interactions form specific niches in the gut and how these niches function at the cellular and molecular level remains unexplored, mainly due to a lack of suitable technologies.To fill this…
KAROLINSKA INSTITUTET
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Sweden, Stockholm
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Leiden University Medical Center
Netherlands, Leiden
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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