CORDIS Project
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This project explores the use of engineered enzymes for the sustainable formation of carbon-carbon bonds in organic synthesis. By focusing on transaminases, it aims to develop biocatalytic methods that enhance efficiency and reduce reliance on toxic materials.
Carbon-carbon (C-C) bond formation is one of the most challenging synthetic reactions in chemistry.
Current approaches require expensive and toxic transition metals with complex ligands that have limited selectivity.
Developing biocatalytic sustainable methods for the controlled formation of C-C bonds with stereospecificity in high yields has the potential to advance organic chemistry and provide access to new molecules.
Although several enzymes are capable of catalyzing C-C bonds, few biocataly…
TECHNISCHE UNIVERSITEIT DELFT
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